General description
TOPflash是β-连环蛋白应答的萤火虫荧光素酶报告基因质粒。
Application
TOPflash(TCF报告基因质粒)已用于在TOP flash报告基因检测中转染培养细胞。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Haijun Zhao et al.
Oncology letters, 21(6), 472-472 (2021-04-29)
Long non-coding (lnc) RNAs have emerged as important regulators of cancer development and progression. Several lncRNAs have been reported to be associated with prostate cancer (PCa); however, the involvement of lncRNA SNHG17 in PCa remains unclear. In the present study
Species differences in kidney necrosis and DNA damage, distribution and glutathione-dependent metabolism of 1,2-dibromo-3-chloropropane (DBCP).
E J S?derlund,M L?g,J A Holme,G Brunborg,J G Omichinski,J E Dahl,S D Nelson,E Dybing
Pharmacology & Toxicology null
Ji Young Choi et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 33(11), 2059-2070 (2018-07-13)
Patients with Hutchinson-Gilford progeria syndrome (HGPS) have low bone mass and an atypical skeletal geometry that manifests in a high risk of fractures. Using both in vitro and in vivo models of HGPS, we demonstrate that defects in the canonical
Sergio Roman-Roman et al.
The Journal of biological chemistry, 279(7), 5725-5733 (2003-11-25)
Activation of the Wnt signaling cascade provides key signals during development and in disease. Wnt signals are transduced by seven-transmembrane Frizzleds (Fzs) and the single transmembrane low density lipoprotein receptor-related proteins 5 or 6. In the course of the analysis
T Ishitani et al.
Nature, 399(6738), 798-802 (1999-07-03)
The Wnt signalling pathway regulates many developmental processes through a complex of beta-catenin and the T-cell factor/lymphoid enhancer factor (TCF/LEF) family of high-mobility-group transcription factors. Wnt stabilizes cytosolic beta-catenin, which then binds to TCF and activates gene transcription. This signalling
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