218753
Caspase-5 Inhibitor I
Single spot by TLC, solid, Caspase-5 inhibitor, Calbiochem®
别名:
Caspase-5 Inhibitor I, Z-WE(OMe)HD(OMe)-FMK
产品名称
Caspase-5 Inhibitor I, Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
caspase-1, caspase-4, caspase-5, caspase-8
caspase-1, caspase-4, caspase-5, caspase-8
Reversible: no
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Analysis Note
single spot by TLC
Other Notes
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持