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Merck
CN

218755

Sigma-Aldrich

Caspase-4 Inhibitor I

The Caspase-4 Inhibitor I, also referenced under CAS 402832-01-3, controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.

别名:

Caspase-4 Inhibitor I, Ac-LEVD-CHO

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关于此项目

经验公式（希尔记法）:
C22H36N4O9
化学文摘社编号:
402832-01-3
分子量:
500.54
MDL编号:
MFCD08703162
UNSPSC代码:
12352200
NACRES:
NA.54

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质量水平

100

方案

≥95% (HPLC)

表单

lyophilized solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white

溶解性

water: 1 mg/mL

运输

ambient

储存温度

−20°C

SMILES字符串

N([C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)CCC(=O)O

InChI

1S/C22H36N4O9/c1-11(2)8-16(23-13(5)28)21(34)25-15(6-7-17(29)30)20(33)26-19(12(3)4)22(35)24-14(10-27)9-18(31)32/h10-12,14-16,19H,6-9H2,1-5H3,(H,23,28)(H,24,35)(H,25,34)(H,26,33)(H,29,30)(H,31,32)/t14-,15-,16-,19-/m0/s1

InChI key

MXGJLIBJKIIQSF-FPXQBCRKSA-N

相关类别

一般描述

A reversible caspase-4 (ICH-2) inhibitor.
A reversible caspase-4 inhibitor.

生化/生理作用

Cell permeable: no
Primary Target
caspase-4
Product does not compete with ATP.
Reversible: yes

制备说明

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Ac-Leu-Glu-Val-Asp-CHO
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Standard Handling (A)

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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