219385
Cathepsin B Inhibitor II
≥95% (HPLC), cathepsin B inhibitor , solid
别名:
Cathepsin B Inhibitor II, Ac-LVK-CHO
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关于此项目
经验公式（希尔记法）:
C19H36N4O4
分子量:
384.51
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
solid
Storage condition:
OK to freeze
产品名称
Cathepsin B Inhibitor II, The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Quality Segment
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−70°C
General description
A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) compared to leupeptin (IC50 = 310 nM).
Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) than of leupeptin (IC50 = 310 nM). Note: this peptide forms cyclic isomers.
Note: this peptide forms cyclic isomers.
Biochem/physiol Actions
Cell permeable: no
Primary Target
cathepsin B
cathepsin B
Product does not compete with ATP.
Reversible: no
Target IC50: 4 nM against cathepsin B
Preparation Note
Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.
Other Notes
Ac-Leu-Val-lysinal
McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
怎么回事？
WGK 1
闪点 (F)
Not applicable
闪点 (°C)
Not applicable