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Cathepsin B Inhibitor II

Name: Cathepsin B Inhibitor II
Brand: MM

≥95% (HPLC), cathepsin B inhibitor , solid

别名:

Cathepsin B Inhibitor II, Ac-LVK-CHO

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关于此项目

经验公式（希尔记法）:

C₁₉H₃₆N₄O₄

分子量:

384.51

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥95% (HPLC)

Form:

solid

Storage condition:

OK to freeze

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属性

产品名称

Cathepsin B Inhibitor II, The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Quality Segment

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−70°C

说明

General description

A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) compared to leupeptin (IC₅₀ = 310 nM).

Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) than of leupeptin (IC₅₀ = 310 nM). Note: this peptide forms cyclic isomers.

Note: this peptide forms cyclic isomers.

Biochem/physiol Actions

Cell permeable: no

Primary Target
cathepsin B

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 4 nM against cathepsin B

Preparation Note

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

Other Notes

Ac-Leu-Val-lysinal

McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c