220202
CHAPSO
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
别名:
CHAPSO, 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
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关于此项目
经验公式（希尔记法）:
C32H58N2O8S
化学文摘社编号:
分子量:
630.88
UNSPSC Code:
12161902
NACRES:
NA.25
MDL number:
SMILES string
[S](=O)(=O)([O-])CC(O)C[N+](CCCNC(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)C[C@@H]2O)CC1)C)C)(C)C
InChI
1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
InChI key
GUQQBLRVXOUDTN-XOHPMCGNSA-N
assay
>98% (TLC)
form
solid
mol wt
micellar wt 9960
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
aggregation number
11
color
white
CMC
8 mM
solubility
water: soluble
shipped in
ambient
storage temp.
2-8°C
Quality Level
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General description
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state (aggregation number: 11; CMC: 8 mM; micellar weight: 9960). Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Has a higher solubility than CHAPS because of its more polar head group.
Preparation Note
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 days at 4°C.
Other Notes
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA77, 4623.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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