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Merck
CN

220411

Chenodeoxycholic Acid, Sodium Salt

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

别名:

Chenodeoxycholic Acid, Sodium Salt

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关于此项目

经验公式(希尔记法):
C24H39O4 · Na
化学文摘社编号:
分子量:
414.55
UNSPSC Code:
12161902
NACRES:
NA.21
MDL number:
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产品名称

Chenodeoxycholic Acid, Sodium Salt, Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

SMILES string

[Na+].[O-]C(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)CC2)CC1)C)C

InChI

1S/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;/m1./s1

InChI key

WDFRNBJHDMUMBL-OICFXQLMSA-M

description

Merck USA index - 14, 2054

assay

>95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: 20 mg/mL
aqueous buffer: soluble

cation traces

heavy metals: <10 ppm

shipped in

ambient

storage temp.

15-25°C

Quality Level

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

General description

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

Other Notes

Rolo, A.P., et al. 2001. Biosci. Rep.21, 73.
Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
Roda, A., et al. 1990. J. Lipid Res.31, 1433.
Spivak, W., et al. 1988. Biochem. J.252, 275.
Hisadome, T., et al. 1980. Gastroenterol. Jpn.15, 257.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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