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Merck
CN
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About This Item

UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.41
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生物来源

human

质量水平

重组

expressed in baculovirus infected Sf21 cells

制造商/商品名称

Upstate®

技术

activity assay: suitable

NCBI登记号

一般描述

Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal transduction pathways, Src activity is tightly controlled through reversible phosphorylation and dephosphorylation events and down-regulation by ubiquitin-dependent degradation. Dysfunction of Src, through overexpression or increased activation has profound effects on basic cellular functions. Elevated Src expression and/or activation is evident across a wide range of solid tumour types and has been strongly implicated in the development, maintenance, progression, and metastatic spread of several human cancers, such as prostate, lung, breast, and colorectal cancer.

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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