form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
color
clear yellow
shipped in
dry ice
storage temp.
−70°C
Quality Level
Application
Complement C3-Depleted Serum, Human has been used to study its effects on the α-secretase activity of umbilical cord blood serum (CBS).
Disclaimer
Toxicity: Standard Handling (A)
General description
Complement C3-depleted serum is a human serum that is depleted of complement component C3. It is prepared from serum that has been shown by certified tests to be negative for Hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C virus (HCV), human immunodeficiency virus (HIV-I), and HIV-II.
Other Notes
Classical Pathway Activity: One C3H50 unit measured by classical pathway activation is defined as the amount of C3 required to yield 50% lysis of 3 x 10⁷ EA when incubated in the presence of the recommended volume of C3-Dpl for 30 min at 37°C in a total reaction volume of 500 µl GVB++.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 150 mM NaCl, 50 mM sodium phosphate, pH 7.2.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HCV, HIV-I, and HIV-II.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品-Merck
此项目有
Ahsan Habib et al.
Cell transplantation, 27(4), 666-676 (2018-06-07)
Alzheimer's Disease (AD) is the leading cause of dementia in the elderly. In healthy individuals, amyloid precursor protein (APP) is cleaved by α-secretase, generating soluble α-amyloid precursor protein (sAPPα), which contributes neuroprotective functions in the neuronal environment. In contrast, in
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