238470
聚氧乙烯蓖麻油 -CAS 61791-12-6-Calbiochem
别名:
Cremophor® EL
SMILES string
ClCC(OC(=O)N)CCl
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
clear pale yellow
CMC
~0.02%
solubility
ethanol: soluble, water: soluble, clear (at higher temperatures the solution will be come turbid)
density
1,050 g/cm3
application(s)
(Excipient in drug)
shipped in
ambient
storage temp.
2-8°C
Quality Level
General description
1 组 = 5 X 25 GM
亲水-亲脂平衡（HLB）〜12-14。
通过使蓖麻油与环氧乙烷以 1:35 的摩尔比反应来形成聚氧乙烯化甘油三酸酯的混合物，该混合物可作为非离子表面活性剂，并用作水溶性差的药理剂的配制载体（口服和静脉内给药）。
Application
- Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.：本文研究长爪沙鼠应用类胡萝卜素和视黄醇后的蛋白质变化。Cremophor® EL作为这些化合物的增溶剂，体现它在涉及脂溶性物质的生化研究中的作用(Bohn et al., 2018)。
Packaging
用惰性气体包装
Other Notes
Gelderblom, H., et al. 2001.Eur. J. Cancer37, 1590.
Sparreboom, A., et al. 1996.Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990.Cancer Res.50, 4199.
Sparreboom, A., et al. 1996.Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990.Cancer Res.50, 4199.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Cremophor is a registered trademark of BASF SE
Disclaimer
毒性：标准处理（A）
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
494.6 °F - Not applicable
flash_point_c
257 °C - Not applicable
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