239900
Cypermethrin
Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
别名:
Cypermethrin
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关于此项目
经验公式（希尔记法）:
C22H19Cl2NO3
化学文摘社编号:
分子量:
416.30
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
oil
Storage condition:
OK to freeze
description
Merck USA index - 14, 2767
Quality Segment
assay
≥95% (HPLC)
form
oil
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
DMSO: 15 mg/mL, ethanol: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
ClC(=CC1C(C1C(=O)OC(c2cc(ccc2)Oc3ccccc3)C#N)(C)C)Cl
InChI
1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
InChI key
KAATUXNTWXVJKI-UHFFFAOYSA-N
General description
Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 40 pM). May also have varied effects on ion channels.
Biochem/physiol Actions
Primary Target
calcineurin
calcineurin
Product does not compete with ATP.
Target IC50: 40 pM against calcineurin (protein phosphatase 2B
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Toxic (F)
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警示词
Warning
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
靶器官
Nervous system, Respiratory system
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
212.0 °F - closed cup
闪点 (°C)
100 °C - closed cup