SMILES string
S(SC[C@H]([N+H3])C(=O)[O-])C[C@H]([N+H3])C(=O)[O-]
InChI
1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChI key
LEVWYRKDKASIDU-IMJSIDKUSA-N
assay
≥98% (Macro-Kjeldahl method)
form
crystalline powder
crystals
optical activity
[α]20/D -218 to -224°, c = 2 in 1 M HCl
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
anion traces
chloride (Cl-): ≤0.02%
sulfate (SO42-): ≤0.02%
cation traces
As: ≤1 ppm
NH4+: ≤0.02%
heavy metals: ≤10 ppm
shipped in
ambient
storage temp.
15-25°C
Quality Level
Disclaimer
Toxicity: Standard Handling (A)
General description
Non-essential amino acid for human development. Has an optimal pH of 5.0-6.5.
Preparation Note
Solubility may be enhanced by lowering the pH to <2.0 or raising the pH to >8.0.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Gregory R Kardos et al.
Frontiers in oncology, 10, 834-834 (2020-07-09)
Increased protein synthesis is a key process in melanoma, which is regulated by the ALDH18A1 gene encoding pyrroline-5-carboxylate synthase (P5CS). P5CS is involved in proline biosynthesis and targeting ALDH18A1 has previously been shown to inhibit melanoma development by decreasing intracellular
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