Name: 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride
Brand: MM

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About This Item

UNSPSC代码:

12352200

NACRES:

NA.77

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Product Name

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, Effective irreversible inhibitor of uPA, Factor Xa, and urokinase.

质量水平

100

表单

solid

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze
desiccated

颜色

off-white

溶解性

soluble (Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.)

运输

ambient

储存温度

2-8°C

一般描述

Effective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.

生化/生理作用

Cell permeable: no

Primary Target
UPA

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 100 nM for factor Xa

制备说明

Following initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.

Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.

其他说明

Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Standard Handling (A)

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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