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251700

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride

Name: 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride
Brand: MM

UPA inhibitor, solid

别名:

1,5-DNS-GGACK, 2HCl

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关于此项目

UNSPSC Code:

12352200

NACRES:

NA.77

Form:

solid

Storage condition:

OK to freeze, desiccated

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属性

产品名称

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, Effective irreversible inhibitor of uPA, Factor Xa, and urokinase.

Quality Segment

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated

color

off-white

solubility

soluble (Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.)

shipped in

ambient

storage temp.

2-8°C

说明

General description

Effective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.

Biochem/physiol Actions

Cell permeable: no

Primary Target
UPA

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 100 nM for factor Xa

Preparation Note

Following initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.

Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.

Other Notes

Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

怎么回事？

WGK 1

闪点 (F)

Not applicable

闪点 (°C)