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264151

Caspase-3 Substrate VII, Fluorogenic

Name: Caspase-3 Substrate VII, Fluorogenic
Brand: MM

Fluorogenic caspase-3 substrate.

别名:

Caspase-3 Substrate VII, Fluorogenic, Ac-DEVD-AFC

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关于此项目

经验公式（希尔记法）:

C₃₀H₃₄F₃N₅O₁₃

分子量:

729.61

NACRES:

NA.77

UNSPSC Code:

12352200

Assay:

≥95% (HPLC)

Form:

lyophilized solid

Quality level:

100

Storage condition:

OK to freeze, desiccated, protect from light

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属性

Quality Level

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated, protect from light

color

white

solubility

DMSO: 5 mg/mL

fluorescence

λ_ex ~400 nm, λ_em ~505 nm

shipped in

ambient

storage temp.

−20°C

说明

General description

Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10.

Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Fluorogenic caspase-3 substrate

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Asp-Glu-Val-Asp-AFC

Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c