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287810

2′,7′-二氯荧光素二醋酸盐

Name: 2′,7′-二氯荧光素二醋酸盐
Brand: MM

Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) and nitric oxide (•NO) and for the determination of the degree of overall oxidative stress.

别名:

2′,7′-二氯荧光素二醋酸盐, H₂DCFDA, 2ʹ,7ʹ-二氯二氢荧光素二乙酸酯

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关于此项目

经验公式（希尔记法）:

C₂₄H₁₆Cl₂O₇

化学文摘社编号:

4091-99-0

分子量:

487.29

UNSPSC Code:

12352202

NACRES:

NA.25

MDL number:

MFCD00128955

Assay:

≥94% (HPLC)

Form:

crystalline solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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属性

Quality Level

100

assay

≥94% (HPLC)

form

crystalline solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

Clc1cc2c(cc1OC(=O)C)Oc3c(cc(c(c3)OC(=O)C)Cl)C2c4c(cccc4)C(=O)O

InChI

1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)

InChI key

PXEZTIWVRVSYOK-UHFFFAOYSA-N

说明

General description

细胞可透过性荧光探针，可用于检测中性粒细胞和巨噬细胞中的活性氧（ROS）和一氧化氮（NO），测定毒理学现象中的整体氧化应激程度。

Biochem/physiol Actions

主要目的
检测活性氧（ROS）和一氧化氮（•NO）

产品不与ATP竞争。

可逆：否

细胞渗透性：是

Packaging

用惰性气体包装

Preparation Note

溶解后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多3个月。

Other Notes

Crow, J.P. 1997.Nitric Oxide 1, 145.
Ripple, M.O., et al. 1997.J. Natl.Cancer Inst.89, 40.
Caro, A., and Puntarulo, S. 1996.Biochim.Biophys.Acta1291, 245.
Perez-Garcia, F., et al. 1996.Life Sci. 59, 2033.
Ramakrishnan, N., et al. 1996.生物化学。Pharmacol.51, 1443.
Ferrer, A.S., et al. 1990.Anal.生物化学。187, 129.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

毒性：标准处理（A）

存储类别

11 - Combustible Solids

wgk

WGK 3

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Studies have shown that aerosols generated from flavored e-cigarettes contain Reactive Oxygen Species (ROS), promoting oxidative stress-induced damage within pulmonary cells. Our lab investigated the ROS content of e-cigarette vapor generated from disposable flavored e-cigarettes (vape bars) with and without

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Recently, there has been an outbreak associated with the use of e-cigarette or vaping products, associated lung injury (EVALI). The primary components of vaping products, vitamin E acetate (VEA) and medium-chain triglycerides (MCT), may be responsible for acute lung toxicity.

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货号	GTIN
287810-100MG	07790788054298