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Merck
CN

324744-M

Elastase Inhibitor II

The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

别名:

Elastase Inhibitor II, HNE Inhibitor, MeOSuc-AAPA-CMK, MSACK

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关于此项目

经验公式(希尔记法):
C20H31ClN4O7
分子量:
474.94
NACRES:
NA.77
UNSPSC Code:
12352200
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assay

≥99% (TLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

white

solubility

DMSO: 10 mg/mL, methanol: soluble

storage temp.

−20°C

Quality Level

General description

A potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His57 and Ser195 in the HNE in the presence of this inhibitor.
A potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His57 and Ser195.

Biochem/physiol Actions

Primary Target
Human neutrophil elastase (HNE)

Preparation Note

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Other Notes

MeOSuc-Ala-Ala-Pro-Ala-CMK
Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem.262, 17178.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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