assay
≥99% (TLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
white
solubility
DMSO: 10 mg/mL, methanol: soluble
storage temp.
−20°C
Quality Level
General description
A potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His57 and Ser195 in the HNE in the presence of this inhibitor.
A potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His57 and Ser195.
Biochem/physiol Actions
Primary Target
Human neutrophil elastase (HNE)
Human neutrophil elastase (HNE)
Preparation Note
Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Other Notes
MeOSuc-Ala-Ala-Pro-Ala-CMK
Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem.262, 17178.
Williams, H.R., et al. 1987. J. Biol. Chem.262, 17178.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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