Quality Segment
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
white
solubility
DMSO: 10 mg/mL, methanol: soluble
shipped in
ambient
storage temp.
−20°C
General description
A potent inhibitor of human leukocyte elastase (HLE) (Ki = 10 µM).
A potent irreversible inhibitor of human leukocyte elastase (HLE)(Ki = 10 µM). Protects against lung injury induced by instillation of elastase.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Human leukocyte elastase (HLE)
Human leukocyte elastase (HLE)
Product does not compete with ATP.
Reversible: no
Target Ki: 10 µM against human leukocyte elastase (HLE)
Preparation Note
Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Fletcher, D.S., et al. 1990. Am. Rev. Respir. Dis.141, 672.
Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.
Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.
MeOSuc-Ala-Ala-Pro-Val-CMK
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable