324870
Anti-α-Epithelial Cell Sodium Channel (20-42) Rabbit pAb
liquid, Calbiochem®
别名:
Anti-α-ENaC
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat
Application:
—
Citations:
1
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human, rat
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(Immunoblotting (1 µg/mL)
Immunoprecipitation )
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SCNN1A(6337)
rat ... Scnn1A(25122)
General description
Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~97 kDa glycosylated α-ENaC protein.
Recognizes the ~97 kDa glycosylated α-ENaC protein.
This Anti-α-Epithelial Cell Sodium Channel (20-42) Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of α-Epithelial Cell Sodium Channel (20-42).
Immunogen
Human
a synthetic peptide [LMKGNKREEQGLGPEPAAPQQPT(C)] corresponding to amino acids 20-42 of human α-epithelial cell sodium channel (α-ENaC), conjugated to carrier protein
Application
Immunoblotting (1 µg/ml)
Immunoprecipitation (see comments)
Immunoprecipitation (see comments)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS, 1 mg/ml BSA.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Benos, D.J., and Stanton, B.A. 1999. J. Physiol. London520, 631.
Mano, I., and Driscoll, M. 1999. Bioessays21, 568.
Fyfe, G.K., et al. 1998. Semin. Nephrol.18, 138.
Mano, I., and Driscoll, M. 1999. Bioessays21, 568.
Fyfe, G.K., et al. 1998. Semin. Nephrol.18, 138.
Does not cross-react with β-ENaC or γ-ENaC. Also reported to work for immunoprecipitation. Variables associated with assay conditions will dictate the optimal working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Qian Wang et al.
The Journal of biological chemistry, 288(1), 264-273 (2012-11-20)
Epithelial sodium channel (ENaC) in the kidneys is critical for Na(+) balance, extracellular volume, and blood pressure. Altered ENaC function is associated with respiratory disorders, pseudohypoaldosteronism type 1, and Liddle syndrome. ENaC is known to interact with components of the
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