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Merck
CN

330200-M

Ecotin, E. coli

A potent, broad range inhibitor of serine proteases.

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关于此项目

NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥90% (SDS-PAGE)
Form:
liquid
Quality level:
Storage condition:
OK to freeze, avoid repeated freeze/thaw cycles
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Quality Level

assay

≥90% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage temp.

−70°C

General description

A potent, broad range inhibitor of serine proteases.
A potent, broad range inhibitor or serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also an effective inhibitor of collagenase and granzyme B.

Biochem/physiol Actions

Primary Target
serine proteases
Product does not compete with ATP.
Target IC50: 1 pM against serine proteases
binds trypsin in the picomolar range

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 1.0 mM HCl.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

McGrath, M.E., et al. 1995. Protein Sci. 4, 141.
Seong, I.S., et al. 1994. J. Biol. Chem. 269, 21915.
McGrath, M.E., et al. 1991. J. Biol. Chem. 266, 6620.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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全球贸易项目编号

货号GTIN
330200-100UG04055977195736