产品名称
Anti-Factor B Goat pAb, liquid, Calbiochem®
form
liquid
biological source
goat
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
availability
not available in Canada
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(Immunoelectrophoresis
Radial Immunodiffusion
Ouchterlony (undiluted))
isotype
IgG
shipped in
ambient
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CFB(629)
Application
Immunoelectrophoresis (see comments)
Radial Immunodiffusion (see comments)
Ouchterlony (≥ undiluted)
Radial Immunodiffusion (see comments)
Ouchterlony (≥ undiluted)
Disclaimer
Toxicity: Standard Handling (A)
General description
Goat polyclonal antibody supplied as undiluted serum. Recognizes Factor B.
Recognizes Factor B.
This Anti-Factor B Goat pAb is validated for use in Immunoelectrophoresis, Radial Immunodiffusion, Ouchterlony for the detection of Factor B.
Immunogen
Human
purified, human factor B
Other Notes
This antibody has also been reported to work for immunoelectrophoresis and radial immunodiffusion. Variables associated with assay conditions will dictate the proper working dilution.
Packaging
Please refer to vial label for lot-specific concentration.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Anna M Blom et al.
Journal of clinical immunology, 36(5), 517-527 (2016-05-06)
Autoantibodies termed C3-nephritic factor (C3NeF), which stabilize convertases of the alternative complement pathway, often stimulate autoinflammatory diseases. However, knowledge about analogous autoantibodies acting on the classical pathway (C4NeF) is limited to a few reports, which indicate association with kidney dysfunction
C Duehrkop et al.
Laboratory animals, 48(2), 143-154 (2014-03-04)
Prolonged ischemia of skeletal muscle tissue, followed by reperfusion, leads to ischemia/reperfusion injury (IRI), which is a feared local and systemic inflammatory reaction. With respect to the 3Rs, we wanted to determine which parameters for assessment of IRI require a
Claudia Duehrkop et al.
PloS one, 8(8), e72059-e72059 (2013-08-31)
Ischemia/reperfusion injury of lower extremities and associated lung damage may result from thrombotic occlusion, embolism, trauma, or surgical intervention with prolonged ischemia and subsequent restoration of blood flow. This clinical entity is characterized by high morbidity and mortality. Deprivation of
Diana Pauly et al.
Cell reports, 29(9), 2835-2848 (2019-11-28)
Complement dysregulation is a feature of many retinal diseases, yet mechanistic understanding at the cellular level is limited. Given this knowledge gap about which retinal cells express complement, we performed single-cell RNA sequencing on ∼92,000 mouse retinal cells and validated
Filippo Mori et al.
Frontiers in immunology, 15, 1334151-1334151 (2024-06-26)
Complement factor H (FH) is a major regulator of the complement alternative pathway, its mutations predispose to an uncontrolled activation in the kidney and on blood cells and to secondary C3 deficiency. Plasma exchange has been used to correct for
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