341283
Factor P, Human
Factor P, Human, is a native glycoprotein found in di-, tri-, and tetrameric form (92, 138 & 184 kDa). Accelerates complement activation by binding to and stabilizing the C3 and C5 convertases.
别名:
Properdin
Quality Level
assay
≥90% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
impurities
IgG, IgA, IgM, Factor I, Factor B, Factor H, C3, C4, or albumin, trace (Ouchterlony)
shipped in
wet ice
storage temp.
−70°C
General description
Native factor P from human serum. Glycoprotein found in circulating blood plasma in dimeric, trimeric, and tetrameric forms with M.W. of ~92 kDa, ~138 kDa, and ~184 kDa, respectively. Present in normal human serum at about 20 µg/ml. Regulatory protein of the alternative pathway of complement activation. Accelerates complement activation by binding to and stabilizing the alternative pathway C3 and C5 convertase enzymes.
Physical form
In PBS, pH 7.2.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Pangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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