Fetuin, Fetal Bovine Serum

Native fetuin from fetal bovine serum. α₁-Globulin present in amounts of 40-50% of total serum protein. After birth it is reduced to 40 mg/100 ml. Important supplement to many serum-free media. Inhibits trypsin activity and promotes cell attachment, growth, and differentiation in many different culture systems. Also contains both N- and O-glycosidically linked carbohydrates. Functions as an opsonin for cationic-deactivating molecules in macrophages. Product must not come in contact with ruminating animals or swine.

Native fetuin from fetal bovine serum. An α-globulin that inhibits trypsin activity and promotes cell attachment, growth, and differentiation in many different culture systems. Also contains both N- and O-glycosidically-linked carbohydrates. Functions as an opsonin for cationic-deactivating molecules in macrophages.

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 6 months at -20°C or for up to 1 week at 4°C.

Wang, H., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14429.
Nie, Z. 1992. Am. J. Physiol. 263, C551.

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Toxicity: Standard Handling (A)