FGF-II, Mouse, Recombinant, E. coli

Full-length, recombinant, mouse basic fibroblast growth factor expressed in E. coli. A multi-functional factor with chemotactic activity for numerous cell types. It plays a role in the proliferation of neuronal precursors and in neuronal differentiation. A potent angiogenic factor both in vivo and in vitro. Activates phospholipase D in endothelial cells. Mouse FGFII shares 95% identity with human FGFII. Useful for studies of cell activation and signaling.

ED₅₀: ≤0.5 ng/ml as determined by the dose-dependent proliferation of BALB/3T3 cells.

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Avoid freeze/thaw cycles of solutions.

Reconstitute to 100 µg/ml with sterile H₂O.

Coulier, F. et al. 1997. J. Mol Evol.44, 43.
Claus, P. et al., 2003. J. Biol. Chem.278, 749.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Toxicity: Standard Handling (A)