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About This Item
经验公式（希尔记法）:
C20H24N6O3
CAS Number:
分子量:
396.44
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
质量水平
方案
≥97% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
DMSO: 10 mg/mL
运输
ambient
储存温度
2-8°C
SMILES字符串
N(C(C)(C)C)C(=O)Nc1nc2nc(ncc2cc1c3cc(cc(c3)OC)OC)N
InChI
1S/C20H24N6O3/c1-20(2,3)26-19(27)25-17-15(8-12-10-22-18(21)24-16(12)23-17)11-6-13(28-4)9-14(7-11)29-5/h6-10H,1-5H3,(H4,21,22,23,24,25,26,27)
InChI key
NHJSWORVNIOXIT-UHFFFAOYSA-N
一般描述
A cell-permeable pyridopyrimidinyl urea compound that acts a potent, ATP-competitive inhibitor of FGFR (IC50 = 60 nM using FGFR1) with excellent selectivity over PDGFRβ, EGFR, insulin receptor, and c-Src (IC50 >50 µM).
包装
Packaged under inert gas
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Panek, R.L., et al. 1998. J. Pharm. Exp. Ther.286, 569.
Hamby, J.M., et al. 1997. J. Med. Chem.40, 2296.
Hamby, J.M., et al. 1997. J. Med. Chem.40, 2296.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Irritant (B)
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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