343922
5-氟尿嘧啶
≥98% (HPLC), solid, thymidylate synthase inhibitor, Calbiochem®
别名:
5-氟尿嘧啶
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关于此项目
经验公式（希尔记法）:
C4H3FN2O2
化学文摘社编号:
分子量:
130.08
UNSPSC Code:
12171500
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze
产品名称
5-氟尿嘧啶, Potent antitumor agent.
description
Merck USA index - 14, 4181
Quality Segment
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
hot water: 1 mg/mL, methanol: 1 mg/mL, DMF: 5 mg/mL, DMSO: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
Fc1[c]([nH][c]([nH]c1)=O)=O
InChI
1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChI key
GHASVSINZRGABV-UHFFFAOYSA-N
General description
一种抑制氨基异丁酸-丙酮酸氨基转移酶的强效抗肿瘤药。诱导人结肠癌细胞系的凋亡。
强效抗肿瘤药。抑制氨基异丁酸-丙酮酸氨基转移酶。诱导人结肠癌细胞系的凋亡。
Biochem/physiol Actions
主要靶标
氨基异丁酸-丙酮酸氨基转移酶
氨基异丁酸-丙酮酸氨基转移酶
产物不与ATP竞争。
可逆：否
细胞渗透性：否
Preparation Note
复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多3个月。
Other Notes
Pressacco, J., et al. 1996.Br. J. Cancer72, 939.
Shchepotin, I.B., et al. 1994.Anticancer Res.14, 1027.
Shchepotin, I.B., et al. 1994.Anticancer Res.14, 1027.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：有害（C）
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3