344037
cFMS Receptor Inhibitor II - CAS 959860-85-6 - Calbiochem
The cFMS Receptor Inhibitor II, also referenced under CAS 959860-85-6, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
cFMS Receptor Inhibitor II - CAS 959860-85-6 - Calbiochem, 4-(3,4-Dimethylanilino)-7-(4-pyridyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor II
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
Quality Segment
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: 25 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 80 nM). Although equally potent as cFMS Receptor Inhibitor III (Cat. No. 344038) in inhibiting the cFMS-dependent growth of M-NSF-60 cells (IC50 = 0.1 µM), this inhibitor is much more selective against cFMS-independent growth of NSO cells (IC50 >50 µM).
A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 80 nM). Although equally potent as cFMS Receptor Inhibitor III (Cat. No. 344038) in inhibiting the cFMS-dependent growth of M-NSF-60 cells (IC50 = 0.1 µM), this inhibitor is much more selective against cFMS-independent growth of NSO cells (IC50 >50 µM).
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett.17, 6257.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable