表单
solid
储存条件
OK to freeze
溶解性
soluble (DMSO (20 mg/ml) or Ethanol (20 mg/ml))
储存温度
−20°C
一般描述
A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPγS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
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