344845
Fumagillin, Aspergillus fumigatus
Antiprotozoal agent and angiogenesis inhibitor.
别名:
Fumagillin, Aspergillus fumigatus
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C26H34O7
化学文摘社编号:
分子量:
458.54
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
Fumagillin, Aspergillus fumigatus, Antiprotozoal agent and angiogenesis inhibitor.
SMILES string
O1[C@@](C1CC=C(C)C)([C@@H]2[C@]3(OC3)CC[C@H]([C@H]2OC)OC(=O)\C=C\C=C\C=C\C=C\C(=O)O)C
InChI
1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20?,23-,24-,25+,26+/m1/s1
InChI key
NGGMYCMLYOUNGM-IJIYPQOHSA-N
description
Merck USA index - 14, 4286
assay
≥90% (HPLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white to off-white
solubility
methanol: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Primary Target
Methionine amino-peptidase 2
Methionine amino-peptidase 2
Product does not compete with ATP.
Disclaimer
Toxicity: Harmful (C)
General description
An inhibitor of angiogenesis. Has selective cytostatic effects against ras transformed cells (IC50 = 10 pM). Antiprotozoal agent active against sporozoan parasites in bees and myxozoan parasites in fish.
Antiprotozoal agent and angiogenesis inhibitor. Acts as an inhibitor of methionine amino-peptidase 2.
Other Notes
Zhang, P., et al. 2002. J. Biomed. Sci.9, 34.
Stepien, H., et al. 1996. J. Endocrinol.150, 99.
Abrams, J.S., et al. 1994. Cancer74, 1164.
Jenkins, D.C., et al. 1993. Br. J. Cancer68, 856.
Le Querrec, A., et al. 1993. Baillieres Clin. Hematol.6, 711.
Molnar, K. 1993. Acta Vet. Hung. 41, 51.
Kusada, M., et al. 1991. Biochem. Biophys. Res. Commun. 174, 1070.
Brackett, J.M., et al. 1988. J. Agric. Food Chem.36, 762.
Stepien, H., et al. 1996. J. Endocrinol.150, 99.
Abrams, J.S., et al. 1994. Cancer74, 1164.
Jenkins, D.C., et al. 1993. Br. J. Cancer68, 856.
Le Querrec, A., et al. 1993. Baillieres Clin. Hematol.6, 711.
Molnar, K. 1993. Acta Vet. Hung. 41, 51.
Kusada, M., et al. 1991. Biochem. Biophys. Res. Commun. 174, 1070.
Brackett, J.M., et al. 1988. J. Agric. Food Chem.36, 762.
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持