345752
Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilk
Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma.
别名:
Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk, Neu5Acα2,8Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, 2NH4
产品名称
Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilk, Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma.
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
water: 1 mg/mL
chloroform/methanol (2:1): soluble
shipped in
ambient
storage temp.
−20°C
Quality Level
Disclaimer
Toxicity: Irritant (B)
General description
Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Reported to disrupt mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. Antibodies to GD3 can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. M.W. 1577.0 (based on tricosanoyl - 23:0).
Other Notes
DeMaria, R., et al. 1997. Science 277, 1652.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Sumeyye Cavdarli et al.
Cells, 10(6) (2021-07-03)
The O-acetylated form of GD2, almost exclusively expressed in cancerous tissues, is considered to be a promising therapeutic target for neuroectoderm-derived tumors, especially for breast cancer. Our recent data have shown that 9-O-acetylated GD2 (9-OAcGD2) is the major O-acetylated ganglioside
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持