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Merck
CN

345810

Millipore

G 418 硫酸盐，经细胞培养测试，大包装

G418 also known as Geneticin is an aminoglycoside antibiotic related to Gentamicin. Used as a selective agent in transfection of eukaryotic cells. Has highest potency ≥730 µg/mg and purity ≥98%.

别名:

G 418 硫酸盐，经细胞培养测试，大包装, G418，G 418，NMD抑制剂I

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关于此项目

经验公式（希尔记法）:
C20H40N4O10 · 2H2SO4
CAS Number:
108321-42-2
分子量:
692.71
MDL编号:
MFCD00058314
UNSPSC代码:
12352200

主要文件

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质量水平

100

方案

≥98% (TLC)

表单

powder

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

杂质

≤1.0% Ammonia

颜色

white

溶解性

water: 100 mg/mL, clear, colorless

痕量阳离子

heavy metals: ≤100 ppm

运输

ambient

储存温度

10-30°C

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

一般描述

也提供无菌过滤水溶液（货号 345812），在 100 mM HEPES 中的无菌过滤溶液（货号 508940）和无菌过滤溶液 PBS（货号509227）中的25 mM溶液。

制备说明

重悬后，通过 0.22 µm 或 0.45 µm 孔径的过滤器过滤，等分并冷冻（-20°C）（长期储存），或冷藏（4°C）（短期储存）。无菌储备溶液在 -20°C 下可稳定保存长达 1 年。

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

毒性：标准处理（A）

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H317,H334

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Qin Zhou et al.
Biotechnology journal, 16(9), e2000623-e2000623 (2021-05-31)
Chinese hamster ovary (CHO) cells with a high viable cell density (VCD), resilience to culture stress, and the capacity to continuously express recombinant proteins are highly desirable. Phosphatase and tension homology deleted on chromosome ten (PTEN) functions as a key
Transgene control engineering in mammalian cells.
Beat P Kramer et al.
Methods in molecular biology (Clifton, N.J.), 308, 123-143 (2005-08-06)
Wilfried Weber et al.
Methods in molecular biology (Clifton, N.J.), 267, 451-466 (2004-07-23)
Inducible expression of desired transgenes in mammalian cells and animals is a current priority in basic and applied research, biopharmaceutical manufacturing, gene therapy, and tissue engineering, as well as in drug discovery. Among the most prominent human-compatible transgene control technologies
Jiacheng Lin et al.
PLoS pathogens, 18(1), e1010204-e1010204 (2022-01-15)
The hepatitis B virus (HBV) core protein (HBc) functions in multiple steps of the viral life cycle. Heteroaryldihydropyrimidine compounds (HAPs) such as Bay41-4109 are capsid protein allosteric modulators that accelerate HBc degradation and inhibit the virion secretion of HBV, specifically
Yao Fan et al.
Cell death & disease, 13(4), 404-404 (2022-04-27)
Hepatitis B virus infection remains a major health problem worldwide due to its high risk of liver failure and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA), which is present as an individual minichromosome, serves as the template for transcription of
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