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Merck
CN

3542

谷胱甘肽，氧化型，游离酸

≥95% (HPLC), Antioxidant, solid

别名:

谷胱甘肽，氧化型，游离酸, 环状（γ-Glu-Cys-Gly）₂，GSSG

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关于此项目

经验公式（希尔记法）:
C20H32N6O12S2
化学文摘社编号:
27025-41-8
分子量:
612.63
UNSPSC Code:
12352209
NACRES:
NA.25
MDL number:
MFCD00063106

主要文件

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产品名称

谷胱甘肽，氧化型，游离酸, Glutathione, Oxidized, Free Acid, CAS 27025-41-8, forms a "redox buffer" in physiological systems in the presence of reduced glutathione.

SMILES string

S(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)CC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)

InChI key

YPZRWBKMTBYPTK-UHFFFAOYSA-N

description

RTECS - MC0556500
Merck USA index - 14, 4475

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 1 mg/mL
DMF: 10 mg/mL
ethanol: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

200

相关类别

Disclaimer

毒性：刺激性（B）

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Features and Benefits

  • Cell permeable: no
  • Product does not compete with ATP
  • Reversible: no

General description

Glutathione disulfide (GSSG) is the oxidized form of glutathione (GSH), an antioxidant containing cysteine, glycine, and glutamic acid. GSSG is composed of two reduced GSH molecules linked by a disulfide bond. GSSG plays an essential role in cellular redox balance, and protection against oxidative stress. The reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratio serves as an indicator of oxidative stress. It is involved in various biochemical processes, including the regulation of immune function and metabolism.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Xiulan Shao et al.
Oncology letters, 21(6), 431-431 (2021-04-20)
Ovarian cancer is one of the leading causes of cancer-related death among women worldwide and accounts for 4% of all cancer cases in female patients. To date, ovarian cancer has the poorest prognosis among all types of gynecological cancer; thus

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