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Merck
CN

3542

谷胱甘肽,氧化型,游离酸

≥95% (HPLC), Antioxidant, solid

别名:

谷胱甘肽,氧化型,游离酸, 环状(γ-Glu-Cys-Gly)₂,GSSG

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关于此项目

经验公式(希尔记法):
C20H32N6O12S2
化学文摘社编号:
分子量:
612.63
UNSPSC Code:
12352209
NACRES:
NA.25
MDL number:
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产品名称

谷胱甘肽,氧化型,游离酸, Glutathione, Oxidized, Free Acid, CAS 27025-41-8, forms a "redox buffer" in physiological systems in the presence of reduced glutathione.

SMILES string

S(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)CC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)

InChI key

YPZRWBKMTBYPTK-UHFFFAOYSA-N

description

RTECS - MC0556500
Merck USA index - 14, 4475

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 1 mg/mL, DMF: 10 mg/mL, ethanol: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

General description

Glutathione disulfide (GSSG) is the oxidized form of glutathione (GSH), an antioxidant containing cysteine, glycine, and glutamic acid. GSSG is composed of two reduced GSH molecules linked by a disulfide bond. GSSG plays an essential role in cellular redox balance, and protection against oxidative stress. The reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratio serves as an indicator of oxidative stress. It is involved in various biochemical processes, including the regulation of immune function and metabolism.

Features and Benefits

  • Cell permeable: no
  • Product does not compete with ATP
  • Reversible: no

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

毒性:刺激性(B)

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Xiulan Shao et al.
Oncology letters, 21(6), 431-431 (2021-04-20)
Ovarian cancer is one of the leading causes of cancer-related death among women worldwide and accounts for 4% of all cancer cases in female patients. To date, ovarian cancer has the poorest prognosis among all types of gynecological cancer; thus

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