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Merck
CN

36-002

抗磷酸-SGK抗体

serum, Upstate®

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

抗磷酸-SGK抗体, serum, Upstate®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pSer422/pThr256)

Quality Level

Gene Information

human ... SGK1(6446)

Analysis Note

对照
PDK活化的SGK样品
用PDK1(目录号14-280)磷酸化未活化的SGK1(目录号14-332)后,通过免疫印迹检测到的磷酸SGK进行常规评估

Application

不推荐与细胞裂解液同用。
抗磷酸化SGK抗体是针对磷酸化SGK的抗体,可用于WB。
研究子类别
PI3K、Akt & mTOR 信号传导
研究类别
信号传导

Biochem/physiol Actions

可识别磷酸化SGK。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

48kda

Immunogen

对应于人SGK1的Ser255/Thr256周围氨基酸的肽

Other Notes

浓度:请参考批次特异性浓缩物的检验报告。

Physical form

含有30%甘油和0.035%叠氮化钠的未纯化全兔抗血清。
未纯化

Preparation Note

自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1


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J Park et al.
The EMBO journal, 18(11), 3024-3033 (1999-06-05)
Serum and glucocorticoid-inducible kinase (SGK) is a novel member of the serine/threonine protein kinase family that is transcriptionally regulated. In this study, we have investigated the regulatory mechanisms that control SGK activity. We have established a peptide kinase assay for
Jian-Bang Xu et al.
Signal transduction and targeted therapy, 9(1), 74-74 (2024-03-26)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection disrupts the epithelial barrier and triggers airway inflammation. The envelope (E) protein, a core virulence structural component of coronaviruses, may play a role in this process. Pathogens could interfere with transepithelial Cl-
Phase II trial of temsirolimus in patients with metastatic breast cancer.
Gini F Fleming,Cynthia X Ma,Dezheng Huo,Husain Sattar,Maria Tretiakova,L Lin,Olwen M Hahn et al.
Breast Cancer Research and Treatment null
Yi-Lin Zhang et al.
Mucosal immunology, 11(4), 1149-1157 (2018-03-17)
Airway epithelial cells harbor the capacity of active Cl- transepithelial transport and play critical roles in modulating innate immunity. However, whether intracellular Cl- accumulation contributes to relentless airway inflammation remains largely unclear. This study showed that, in airway epithelial cells
Joseph R Shaw et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 22(1-4), 69-78 (2008-09-05)
Killifish are euryhaline teleosts that adapt to increased salinity by up regulating CFTR mediated Cl(-) secretion in the gill and opercular membrane. Although many studies have examined the mechanisms responsible for long term (days) adaptation to increased salinity, little is

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