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Merck
CN

36-002

抗磷酸-SGK抗体

serum, Upstate®

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
WB
Citations:
11
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biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pSer422/pThr256)

Quality Level

Gene Information

human ... SGK1(6446)

General description

48kda

Immunogen

对应于人SGK1的Ser255/Thr256周围氨基酸的肽

Application

不推荐与细胞裂解液同用。
抗磷酸化SGK抗体是针对磷酸化SGK的抗体,可用于WB。
研究子类别
PI3K、Akt & mTOR 信号传导
研究类别
信号传导

Biochem/physiol Actions

可识别磷酸化SGK。

Physical form

含有30%甘油和0.035%叠氮化钠的未纯化全兔抗血清。
未纯化

Preparation Note

自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。

Analysis Note

对照
PDK活化的SGK样品
用PDK1(目录号14-280)磷酸化未活化的SGK1(目录号14-332)后,通过免疫印迹检测到的磷酸SGK进行常规评估

Other Notes

浓度:请参考批次特异性浓缩物的检验报告。

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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存储类别

10 - Combustible liquids

wgk

WGK 1


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Joseph R Shaw et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 22(1-4), 69-78 (2008-09-05)
Killifish are euryhaline teleosts that adapt to increased salinity by up regulating CFTR mediated Cl(-) secretion in the gill and opercular membrane. Although many studies have examined the mechanisms responsible for long term (days) adaptation to increased salinity, little is
Jian-Bang Xu et al.
Signal transduction and targeted therapy, 9(1), 74-74 (2024-03-26)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection disrupts the epithelial barrier and triggers airway inflammation. The envelope (E) protein, a core virulence structural component of coronaviruses, may play a role in this process. Pathogens could interfere with transepithelial Cl-
J Park et al.
The EMBO journal, 18(11), 3024-3033 (1999-06-05)
Serum and glucocorticoid-inducible kinase (SGK) is a novel member of the serine/threonine protein kinase family that is transcriptionally regulated. In this study, we have investigated the regulatory mechanisms that control SGK activity. We have established a peptide kinase assay for
Phase II trial of temsirolimus in patients with metastatic breast cancer.
Gini F Fleming,Cynthia X Ma,Dezheng Huo,Husain Sattar,Maria Tretiakova,L Lin,Olwen M Hahn et al.
Breast Cancer Research and Treatment null
Alexandra Hochstetler et al.
Fluids and barriers of the CNS, 20(1), 61-61 (2023-08-19)
Hydrocephalus is a pathological accumulation of cerebrospinal fluid (CSF), leading to ventriculomegaly. Hydrocephalus may be primary or secondary to traumatic brain injury, infection, or intracranial hemorrhage. Regardless of cause, current treatment involves surgery to drain the excess CSF. Importantly, there

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