362338
Glyco-SNAP-1 - Calbiochem
A water-soluble nitric oxide (NO) donor.
别名:
Glyco-SNAP-1 - Calbiochem, N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
assay
≥96% (NMR)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
green
solubility
aqueous buffer: 100 mg/mL, water: 100 mg/mL, methanol: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
A water-soluble and stable nitric oxide (NO) donor (t½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.
A water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.
Biochem/physiol Actions
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
A water-soluble nitric oxide (NO) donor
A water-soluble nitric oxide (NO) donor
Preparation Note
Unstable in solution; reconstitute just prior to use.
Other Notes
Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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