368067-M
Granzyme B Substrate VIII, Colorimetric
A colorimetric substrate for granzyme B (kcat/Km = 6.6 x 10⁴ M⁻¹s⁻¹).
别名:
Granzyme B Substrate VIII, Colorimetric, Ac-IEPD- pNA
InChI key
YXEIIOVAGGAMCZ-UHFFFAOYSA-N
SMILES string
CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)C
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 5 mg/mL
storage temp.
−20°C
Quality Level
General description
A colorimetric substrate for granzyme B (kcat/Km = 6.6 x 104 M-1s-1). Cleavage of pNA is monitored colorimetrically at ~405 nm (ε = 9,160 M-1cm-1).
Biochem/physiol Actions
Primary Target
Colorimetric substrate for granzyme B
Colorimetric substrate for granzyme B
kcat/Km = 6.6 x 104 M⁻¹ sec⁻¹ as substrate for granzyme B
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Ac-Ile-Glu-Pro-Asp-pNA
Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持