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Merck
CN

370656

Guanosine 3′,5′-cyclic Monophosphate, Sodium Salt

Important intracellular second messenger implicated in the action of nitric oxide in many cell types.

别名:

Guanosine 3′,5′-cyclic Monophosphate, Sodium Salt, Cyclic GMP, G-3,5-MP, cGMP, Na

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关于此项目

经验公式（希尔记法）:
C10H11N5O7P · Na
化学文摘社编号:
40732-48-7
分子量:
367.19
UNSPSC Code:
41106305
NACRES:
NA.77
MDL number:
MFCD00038424
Assay:
>98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze
desiccated (hygroscopic)

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产品名称

Guanosine 3′,5′-cyclic Monophosphate, Sodium Salt, Important intracellular second messenger implicated in the action of nitric oxide in many cell types.

SMILES string

[Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2O)[n]3c4nc(nc(c4nc3)[O-])N)CO1)O

InChI

1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

InChI key

KMPIYXNEROUNOG-GWTDSMLYSA-M

description

Merck USA index - 14, 2709

assay

>98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

100

相关类别

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biochem/physiol Actions

Cell permeable: no
Primary Target
Activates protein kinase G
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

An important intracellular second messenger implicated in mediating the action of nitric oxide in many cell types. Found to activate protein kinase G. Suppresses apoptosis in rat ovarian follicles.
Important intracellular second messenger implicated in the action of nitric oxide in many cell types. Activates protein kinase G. Suppresses apoptosis in rat ovarian follicles.

Other Notes

Chun, S.Y., et al. 1995. Endocrinology136, 3120.
Kaupp, U.B., and Koch, K.W. 1992. Annu. Rev. Physiol.54, 153.
Goldberg, N.D., and Haddox, M.K. 1977. Annu. Rev. Biochem. 46, 823.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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