370660
Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt
Cell-permeable cGMP analog that preferentially activates protein kinase G.
别名:
Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt, Dibutyryl-cGMP, Na
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关于此项目
经验公式（希尔记法）:
C18H23N5O9P · Na
化学文摘社编号:
分子量:
507.37
MDL number:
UNSPSC Code:
41106305
NACRES:
NA.77
SMILES string
[Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2OC(=O)CCC)[n]3c4nc(nc(c4nc3)O)NC(=O)CCC)CO1)[O-]
InChI
1S/C18H24N5O9P.Na/c1-3-5-10(24)20-18-21-15-12(16(26)22-18)19-8-23(15)17-14(31-11(25)6-4-2)13-9(30-17)7-29-33(27,28)32-13;/h8-9,13-14,17H,3-7H2,1-2H3,(H,27,28)(H2,20,21,22,24,26);/q;+1/p-1/t9-,13-,14-,17-;/m1./s1
InChI key
MGBPJXVWDGGLKI-GBIKJYCISA-M
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
ethanol: soluble, water: soluble
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
Cell-permeable cGMP analog that preferentially activates protein kinase G. Inhibits thrombin stimulated arachidonic acid release in human platelets.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Cell-permeable cGMP analog that preferentially activates protein kinase G.
Cell-permeable cGMP analog that preferentially activates protein kinase G.
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Other Notes
Sane, D.C., et al. 1989. Biochem. Biophys. Res. Commun.165, 708.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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