371780
GP Antagonist-2A
The GP Antagonist-2A controls the biological activity of GP. This small molecule/inhibitor is primarily used for Neuroscience applications.
别名:
GP Antagonist-2A, RPKPQQDWFDWDWM
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: 25 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
A peptide that selectively inhibits the activation of Gq by M1-muscarinic cholinergic receptors. Also inhibits activation by cholecystokinin receptor in pancreatic acini at 10 µM. Blocks angiotensin II-stimulated sis-inducing factor and STAT3 tyrosine phosphorylation.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Inhibits the activation of Gq by M1-muscarinic cholinergic receptors
Inhibits the activation of Gq by M1-muscarinic cholinergic receptors
Product does not compete with ATP.
Reversible: no
Other Notes
H-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH₂
Hunt, R.A., et al. 1999. Hypertension34, 603.
Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
Mukai, H., et al. 1992. J. Biol. Chem.267, 16237.
Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
Mukai, H., et al. 1992. J. Biol. Chem.267, 16237.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持