3741
氯化血红素
Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.
别名:
氯化血红素
产品名称
氯化血红素, Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.
InChI
1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2
InChI key
GGIDWJQWCUJYRY-UHFFFAOYSA-L
description
Merck USA index - 14, 4644
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
dark purple
solubility
0.1-1.0 M NaOH: soluble
1 N NH4OH: soluble
shipped in
ambient
storage temp.
15-25°C
Quality Level
Analysis Note
通过 TLC 进行匀浆
Application
- Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: 本文讨论了氯化血红素在神经系统疾病中的治疗潜力，揭示了其在减轻基因突变相关细胞毒性方面的作用——这对推进神经退行性疾病的治疗具有重要意义(Hirayanagi K et al., 2021)。
- Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: 本文展示了血红素氯化物在增强光谱分析信号检测中的应用——这对于改进环境和食品科学的分析方法非常重要(López-Castaños KA et al., 2020)。
Disclaimer
毒性：标准处理（A）
General description
猪来源的含铁化合物，可诱导 H2O2 依赖性脂质过氧化。据报道，可增加肌管的数量和大小以及肌管收缩的频率。诱导血红素加氧酶-1 活性并减少汞化合物引起的肾脏损伤。
猪来源的含铁化合物，可诱导过氧化氢依赖性脂质过氧化。据报道，可增加肌管的数量和大小以及肌管收缩的频率。
Other Notes
Yonega, R., et al. 2000.Toxicol.Lett.116, 223.
Funanage, V.L., et al. 1989.J. Cell.Physiol.141, 591.
Funanage, V.L., et al. 1989.J. Cell.Physiol.141, 591.
Preparation Note
溶液中不稳定；仅在使用前进行重悬。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Kristine Y Tan et al.
The Analyst, 145(10), 3732-3741 (2020-04-30)
In an open microfluidic device, we investigate protein polyacrylamide gel electrophoresis (PAGE) separation performance on single-cell lysate. Single-cell protein electrophoresis is performed in a thin layer of polyacrylamide (PA) gel into which microwells are molded. Individual cells are isolated in
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