3741
氯化血红素
Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.
别名:
氯化血红素
InChI
1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2
InChI key
GGIDWJQWCUJYRY-UHFFFAOYSA-L
description
Merck USA index - 14, 4644
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
dark purple
solubility
0.1-1.0 M NaOH: soluble, 1 N NH4OH: soluble
shipped in
ambient
storage temp.
15-25°C
Quality Level
General description
猪来源的含铁化合物，可诱导 H2O2 依赖性脂质过氧化。据报道，可增加肌管的数量和大小以及肌管收缩的频率。诱导血红素加氧酶-1 活性并减少汞化合物引起的肾脏损伤。
猪来源的含铁化合物，可诱导过氧化氢依赖性脂质过氧化。据报道，可增加肌管的数量和大小以及肌管收缩的频率。
Application
- Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: 本文讨论了氯化血红素在神经系统疾病中的治疗潜力，揭示了其在减轻基因突变相关细胞毒性方面的作用——这对推进神经退行性疾病的治疗具有重要意义(Hirayanagi K et al., 2021)。
- Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: 本文展示了血红素氯化物在增强光谱分析信号检测中的应用——这对于改进环境和食品科学的分析方法非常重要(López-Castaños KA et al., 2020)。
Preparation Note
溶液中不稳定；仅在使用前进行重悬。
Analysis Note
通过 TLC 进行匀浆
Other Notes
Yonega, R., et al. 2000.Toxicol.Lett.116, 223.
Funanage, V.L., et al. 1989.J. Cell.Physiol.141, 591.
Funanage, V.L., et al. 1989.J. Cell.Physiol.141, 591.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：标准处理（A）
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Kristine Y Tan et al.
The Analyst, 145(10), 3732-3741 (2020-04-30)
In an open microfluidic device, we investigate protein polyacrylamide gel electrophoresis (PAGE) separation performance on single-cell lysate. Single-cell protein electrophoresis is performed in a thin layer of polyacrylamide (PA) gel into which microwells are molded. Individual cells are isolated in
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