376817-M
己糖激酶II抑制剂II，3-BP
The Hexokinase II Inhibitor II, 3-BP, also referenced under CAS 1113-59-3, controls the biological activity of Hexokinase II. This small molecule/inhibitor is primarily used for Cell Structure applications.
别名:
己糖激酶II抑制剂II，3-BP
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关于此项目
经验公式（希尔记法）:
C3H3BrO3
化学文摘社编号:
分子量:
166.96
UNSPSC Code:
12352200
EC Index Number:
214-206-5
MDL number:
NACRES:
NA.77
SMILES string
BrCC(=O)C(=O)O
InChI
1S/C3H3BrO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)
InChI key
PRRZDZJYSJLDBS-UHFFFAOYSA-N
description
RTECS - UZ0840000
assay
≥97% (titration)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 100 mg/mL, distilled water: 100 mg/mL
Quality Level
General description
一种细胞可渗透的丙酮酸衍生物，可作为己糖激酶II介导的糖酵解的抑制剂，并在体外培养物中以及在体内小鼠和大鼠中有效抑制肿瘤存活。
Preparation Note
复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多3个月。
Other Notes
Bujis, M., et al. 2009.Invest. New Drugs27, 120.
Chen, Z., et al. 2009.Biochim.Biophys.Acta.1787, 553.
Hulleman, E., et al. 2009.Blood.113, 2014;
Mathupala, S.P., et al. 2009.Semin.Cancer Biol.19, 17.
Pereira da Silva, A.P., et al. 2009.Biochem.J.417, 717.
Yun, J., et al. 2009.Science.325, 1555.
Zhang, X., et al. 2009.Anticancer Res.29, 1443.
Kim, J.S., et al. 2008.J. Bioenerg.Biomembr.40, 607.
Chen, Z., et al. 2009.Biochim.Biophys.Acta.1787, 553.
Hulleman, E., et al. 2009.Blood.113, 2014;
Mathupala, S.P., et al. 2009.Semin.Cancer Biol.19, 17.
Pereira da Silva, A.P., et al. 2009.Biochem.J.417, 717.
Yun, J., et al. 2009.Science.325, 1555.
Zhang, X., et al. 2009.Anticancer Res.29, 1443.
Kim, J.S., et al. 2008.J. Bioenerg.Biomembr.40, 607.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：腐蚀性（L）
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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