386698
Hydrocortisone
≥99% (HPLC), solid, anti-inflammation agent, Calbiochem®
别名:
氢化可的松，色谱标准品, 皮质醇标准液
产品名称
氢化可的松，色谱标准品, Conforms to USP Reference Standard.
SMILES string
O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@]4(CCC(=O)C=C4CC3)C)[C@H](C2)O)CC1)C)C(=O)CO
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key
JYGXADMDTFJGBT-VWUMJDOOSA-N
description
Merck USA index - 14, 4787
assay
≥99% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 10 mg/mL
ethanol: soluble
shipped in
ambient
storage temp.
10-30°C
Quality Level
Preparation Note
在重悬后存放于冰箱（4°C）。储备液可在4°C最长稳定1个月。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Biochem/physiol Actions
产物不与ATP竞争。
可逆：否
细胞渗透性：否
首要靶标
符合美国药典参考标准
符合美国药典参考标准
Disclaimer
毒性：致癌/致畸（D）
General description
符合美国药典参考标准。
类固醇由肾上腺皮质合成。对于蛋白质、核酸和脂质代谢的调节至关重要。在药理上，氢化可的松可用于抑制炎症反应。该制剂符合美国药典参考标准。
signalword
Danger
hcodes
Hazard Classifications
Repr. 1A - STOT RE 2
target_organs
Adrenal gland,Bone marrow
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Fujio Toki et al.
Regenerative therapy, 14, 222-226 (2020-05-22)
Impaired wound healing in critical limb ischemia (CLI) results from multiple factors that affect many cell types and their behavior. Epidermal keratinocytes and dermal fibroblasts play crucial roles in wound healing. However, it remains unclear whether these cell types irreversibly
Sophie Dekoninck et al.
Cell, 181(3), 604-620 (2020-04-08)
During embryonic and postnatal development, organs and tissues grow steadily to achieve their final size at the end of puberty. However, little is known about the cellular dynamics that mediate postnatal growth. By combining in vivo clonal lineage tracing, proliferation kinetics
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