主要文件

查看所有文档

400086

HIF Inhibitor VI

Name: HIF Inhibitor VI
Brand: MM

The HIF-1 Inhibitor, NSC-134754 controls the biological activity of HIF-1. This small molecule/inhibitor is primarily used for Cell Structure applications.

别名:

HIF Inhibitor VI, NSC-134754

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₂₇H₃₄N₂O₂

分子量:

418.57

NACRES:

NA.77

UNSPSC Code:

12352200

Assay:

≥90% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

100

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

brown

solubility

DMSO: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

说明

General description

A cell-permeable emetan derivative that selectively reduces HIF-1 activity by 73% in a luciferase reporter assay, and blocks HIF-1α protein induction in response to DFX, hypoxia, and IGF-1 in U2OS-HRE-luc cells at 10 µM, without significantly inhibiting cell growth. Furthermore, it is shown to completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells.

Packaging

Packaged under inert gas

Other Notes

Chau, N.M., et al. 2005. Cancer Res.65, 4918.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c