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Merck
CN

400120

Human IgG1, Myeloma

别名:

Myeloma IgG₁

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352202
Clone:
-
Species reactivity:
-
Application:
Citations:
5
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assay

>95% (SDS-PAGE)

form

liquid

contains

≤0.1% sodium azide as preservative

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

wet ice

storage temp.

−20°C

Quality Level

General description

Native IgG1 from human myeloma plasma. Purified from plasma of patients with myelomas producing IgG1 with kappa light chains.

Physical form

In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Preparation Note

Prepared from plasma that was shown by certified tests to be negative for HBsAg and for antibodies to HCV, HBc, HIV-1 and HIV-2.

Other Notes

Single arc by immunoelectrophoresis against antiserum to whole human sera and human κ free and bound light chain. Note: the heavy chain of myeloma IgGs may appear as either a single or double band on gel electrophoresis. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

高风险级别生物产品--人源产品
此项目有

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Anna Moroz et al.
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R B Cejas et al.
Scientific reports, 11(1), 10981-10981 (2021-05-28)
Persons with Down syndrome (DS, trisomy 21) have widespread cellular protein trafficking defects. There is a paucity of data describing the intracellular transport of IgG in the context of endosomal-lysosomal alterations linked to trisomy 21. In this study, we analyzed
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