α-Interferon, Mouse, Recombinant, E. coli

Recombinant, mouse α-interferon expressed in E. coli. Antiviral, antineoplastic agent. Expressed during the triggering stage of macrophage cytocidal activation. Suppresses bone marrow function and cell proliferation. Modulates the immune response. Also known to induce apoptotic cell death in non-melanoma skin cancer.

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One unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.

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Toxicity: Standard Handling (A)