γ-Interferon, Human, Recombinant, E. coli

Recombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses. Expressed in and purified from E. coli.

ED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.

Please refer to vial label for lot-specific concentration.

Sterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.

Following initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.

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Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA89, 11964.
Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.

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Toxicity: Standard Handling (A)