407709
胰岛素，锌，人，重组，毕赤酵母
别名:
胰岛素，锌，人，重组，毕赤酵母
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关于此项目
Biological source:
yeast (Pichia pastoris)
Form:
solid
Assay:
≥95—105%
biological source
yeast (Pichia pastoris)
Quality Level
description
Merck USA index - 14, 4980
sterility
non-sterile
assay
≥95—105%
form
solid
specific activity
≥25 IU/mg (dry basis)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<10 EU/mg Endotoxin (EU/mg protein)
color
white to off-white
solubility
0.01 M HCl: soluble
shipped in
wet ice
storage temp.
−20°C
InChI key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
General description
在巴斯德毕赤酵母中表达的重组人胰岛素（锌）。由胰腺β-细胞产生的肽合成代谢激素。增加线粒体内蛋白、脂肪、糖原的合成及底物氧化。与膜胰岛素受体相互作用引起其生物学作用。
Preparation Note
复溶后，储存在冰箱中（4°C）。储备液可在4°C最长稳定6周。
胰岛素在pH值4.5-7.0中几乎不溶。
Other Notes
Mohan, C., et al. 1989.Curr.Topics Cell.Reg.30, 105.
Johnson, I.S.1983.Science219, 632.
Johnson, I.S.1983.Science219, 632.
≥25 IU/mg (dry basis).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：标准处理（A）
存储类别
11 - Combustible Solids
wgk
nwg
法规信息
高风险级别生物产品-Merck
此项目有
Mohan Sreelekshmi et al.
Journal of biochemical and molecular toxicology, 35(6), 1-8 (2021-03-03)
Glucokinase (GK), a key regulator of hepatic glucose metabolism in the liver and glucose sensor and mediator in the secretion of insulin in the pancreas, is not studied in detail for its therapeutic application in diabetes. Herein, we study the
Kapil Manglani et al.
Cell biology international, 46(3), 488-497 (2021-12-06)
Role of CDK5 and its inhibition in various neuronal processes and functions are well established. However, role of CDK5 and its inhibition in neuronal insulin-signaling and-resistance is not yet explored. In the present study, we investigated the effect of CDK5
Yamini Yadav et al.
The FEBS journal, 289(23), 7561-7581 (2022-07-11)
PP2Cα is one of the newly identified isoforms of metal-dependent protein phosphatases (PPM). The role of this phosphatase in neuronal insulin signalling is completely unknown. In the present study, we show insulin-mediated rapid upregulation of a protein of the insulin
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 407709-50MG | 07790788050047 |