407710
α-碘乙酰胺
≥99% (HPLC), crystalline solid, cysteine protease inhibitor, Calbiochem®
别名:
α-碘乙酰胺
产品名称
α-碘乙酰胺, α-Iodoacetamide, CAS 144-48-9, is an irreversible inhibitor of several cysteine proteases.
SMILES string
ICC(=O)N
InChI
1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI key
PGLTVOMIXTUURA-UHFFFAOYSA-N
description
RTECS - AC4200000
assay
≥99% (HPLC)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white
solubility
methanol: 1:20
DMF: soluble
ethanol: soluble
water: soluble
shipped in
ambient
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
主要靶标
半胱氨酸蛋白酶
半胱氨酸蛋白酶
产物不与ATP竞争。
可逆：否
细胞渗透性：否
Disclaimer
毒性：有毒（F）
General description
几种半胱氨酸蛋白酶的不可逆抑制剂。可用于烷基化半胱氨酸和蛋氨酸残基。
Other Notes
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Preparation Note
溶液中不稳定；仅在使用前进行复溶。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Sukanya Mozumder et al.
Bio-protocol, 10(15), e3704-e3704 (2021-03-05)
The serotonin 5-HT2A receptor (5-HT2AR) is a member of the GPCR family that is important for various neurological functions and whose dysregulation causes many mental health disorders. Structural investigations of 5-HT2AR require the production of functionally active receptors expressed from
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