420123-M
JNK Inhibitor II, Negative Control
The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
JNK Inhibitor II, Negative Control, N¹-Methyl-1,9-pyrazoloanthrone
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关于此项目
经验公式（希尔记法）:
C15H10N2O
化学文摘社编号:
分子量:
234.25
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.28
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: 10 mg/mL
storage temp.
−20°C
Quality Level
General description
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 µM and 24 µM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively).
Biochem/physiol Actions
Primary Target
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)
Target IC50: 18 µM and 24 µM against JNK2 and JNK3, respectively
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.
Other Notes
Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta1589, 311.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA98, 13681.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA98, 13681.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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