420307
激肽释放酶，人血浆
Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.
别名:
激肽释放酶，人血浆
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
Specific activity:
≥15 units/mg protein
Assay:
≥95% (SDS-PAGE)
Biological source:
human plasma
产品名称
激肽释放酶，人血浆, Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.
biological source
human plasma
description
Merck USA index - 14, 5279
assay
≥95% (SDS-PAGE)
form
liquid
specific activity
≥15 units/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
storage temp.
−20°C
Quality Level
Disclaimer
仅供研究使用在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。
毒性：有害（C）
General description
来自人血浆的天然激肽释放酶。一种从激肽原释放缓激肽的丝氨酸蛋白酶。存在于血浆中作为非活性前体激肽释放酶原。
Other Notes
Pu, X., et al. 1994.Biochim.Biophys.Acta 1208, 338.
Nagase, H. and Barrett, A.J.1981.Biochem.J.193, 187.
Nagase, H. and Barrett, A.J.1981.Biochem.J.193, 187.
一个单位定义为在25°C，pH 8.0下，每分钟水解1.0 µmol D-Pro-Phe-Arg-pNA的酶量。
Packaging
请参考特定浓度批号的标签。
Physical form
在NaCl和Tris-HCl缓冲液中。
Preparation Note
初次融化后，等分并冷冻（-20°C）。
由经认证测试对HBsAg以及HIV和HCV抗体阴性的血浆制备而成。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品-Merck
此项目有
Ning Luan et al.
Toxins, 11(12) (2019-12-11)
Elastase is a globular glycoprotein and belongs to the chymotrypsin family. It is involved in several inflammatory cascades on the basis of cleaving the important connective tissue protein elastin, and is strictly regulated to a balance by several endogenous inhibitors.
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