420311
硫酸卡那霉素，来源于卡那链霉菌
An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms.
别名:
硫酸卡那霉素，来源于卡那链霉菌
InChI key
OOYGSFOGFJDDHP-KMCOLRRFSA-N
InChI
1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to off-white
solubility
water: 10 mg/mL
shipped in
ambient
storage temp.
10-30°C
Quality Level
General description
功效：≥750 µg/mg
包含超过 98％ 的卡那霉素 A。一种对氨基葡萄糖革兰氏阳性和革兰氏阴性生物有效的氨基糖苷类抗生素。作用于 70S 核糖体的蛋白质生物合成的抑制剂，导致对遗传密码的误读。可能引起肾脏损害和耳毒性。
Biochem/physiol Actions
主靶
蛋白生物合成
蛋白生物合成
Preparation Note
重悬后，通过 0.22 µm 孔径的过滤器过滤灭菌，等分并冷冻（-20°C）。储备液可在-20°C最长稳定1个月。
Other Notes
Lech, K., and Brent, R. 1995. in Current Protocols in Mol.Biol. Vol. 1 (Ausubel, F.M., et al., eds.)John Wiley & Sons, New York.
Kahn, R.W., et al. 1993.Proc.Natl.Acad.Sci. USA90, 9295.
Cardon, G.H., et al. 1993.Plant J.3, 773.
Maniatis, T., et al. 1989.In Molecular Cloning, A Laboratory Manual, Second Edition.Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978.In Antibiotics, Origin, Nature, and Properties1, 690.
Stiffler, P.W., et al. 1974.《抗菌药物和Agents Chemother.6, 516.
Umezawa, S., et al. 1968.J. Antibiot.21, 367.
Kahn, R.W., et al. 1993.Proc.Natl.Acad.Sci. USA90, 9295.
Cardon, G.H., et al. 1993.Plant J.3, 773.
Maniatis, T., et al. 1989.In Molecular Cloning, A Laboratory Manual, Second Edition.Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978.In Antibiotics, Origin, Nature, and Properties1, 690.
Stiffler, P.W., et al. 1974.《抗菌药物和Agents Chemother.6, 516.
Umezawa, S., et al. 1968.J. Antibiot.21, 367.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
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