422686
Kininogen, High Molecular Weight, Single Chain, Human Plasma
Native, single chain, high molecular weight Kininogen from human plasma.
别名:
High molecular weight kininogen
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关于此项目
NACRES:
NA.28
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)
Quality Segment
assay
≥95% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−70°C
General description
Native, single chain, high molecular weight Kininogen from human plasma. Nonenzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor α-XIIa. Also circulates in plasma in complex with Factor XI and may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Weisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable