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Merck
CN

427572

Bovine Lactosyl Ceramide

≥98% (TLC), solid, glycosphingolipid precursor, Calbiochem®

别名:

Lactosyl Ceramide, Bovine, Galβ,1,4Glc-Cer, LacCer, LC, LC, Galβ,1,4Glc-Cer, LacCer

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关于此项目

经验公式（希尔记法）:
C53H101NO13
化学文摘社编号:
4682-48-8
分子量:
960.37
UNSPSC Code:
12352211
NACRES:
NA.77
MDL number:
MFCD00133445
Assay:
≥98% (TLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze

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产品名称

Lactosyl Ceramide, Bovine, A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL.

SMILES string

N(C(C(O)\C=C\CCCCCCCCCCCCC)CO[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)OC2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO)CO)C(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1

InChI key

VOZHMDQUIRUFQW-AIRKALMMSA-N

description

RTECS - FK1000000

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

colorless

solubility

ethanol: 1 mM, methanol: 1 mM

shipped in

ambient

storage temp.

−20°C

Quality Level

100

相关类别

General description

A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.
A neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fos expression in human aortic smooth muscle cells.



Molecular weight: 960.4 (based on tricosanyl -23:0)
M.W. 960.4 (based on tricosanoyl - 23:0).

Biochem/physiol Actions

Cell permeable: no
Primary Target
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Other Notes

Bhunia, A.K., et al. 1997. J. Biol. Chem.272, 15642.
Bhunia, A.K., et al. 1996. J. Biol. Chem.271, 10660.
Zacharias, C., et al. 1994. J. Biol. Chem.269, 13313.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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